Raw Galantamine Hydrobromide powder (69353-21-5) Manufacturers - Phcoker Chemical
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Galantamine Hydrobromide (69353-21-5) Description
Galantamine hydrobromide is a benzazepine derived from norbelladine. It is found in GALANTHUS and other AMARYLLIDACEAE. It is a cholinesterase inhibitor that has been used to reverse the muscular effects of GALLAMINE TRIETHIODIDE and TUBOCURARINE and has been studied as a treatment for ALZHEIMER DISEASE and other central nervous system disorders.
Galantamine Hydrobromide is the hydrobromide salt form of galantamine, a tertiary alkaloid obtained synthetically or naturally from the bulbs and flowers of Narcissus and several other genera of the Amaryllidaceae family with anticholinesterase and neurocognitive-enhancing activities. Galantamine competitively and reversibly inhibits acetylcholinesterase, thereby increasing the concentration and enhancing the action of acetylcholine (Ach). In addition, galantamine is a ligand for nicotinic acetylcholine receptors, which may increase the presynaptic release of Ach and activate postsynaptic receptors. This agent may improve neurocognitive function in mild and moderate Alzheimer' s disease and may reduce abstinence-induced cognitive symptoms that promote smoking relapse.
Galantamine Hydrobromide (69353-21-5) Specifications
Product Name
Galantamine Hydrobromide
Chemical Name
Galantamin; Galantamine; Galanthamine
Galanthamine Hydrobromide; Lycoremine; Nivalin
Nivaline; Razadyne; Reminyl
Galanthamine hydrobromide; Galantamine hydrobromide; 1953-04-4; Reminyl; Galanthamine (hydrobromide);
Brand Name
No data available
Drug Class
Alzheimer Disease Agents, cholinesterase inhibitor
CAS Number
69353-21-5
InChIKey
QORVDGQLPPAFRS-XPSHAMGMSA-N
Molecular Formula
C17H22BrNO3
Molecular Weight
368.271 g/mol
Monoisotopic Mass
367.078 g/mol
Melting Point
126-127 deg C
Freezing Point
No data available
Biological Half-Life
Elimination half-life: 7 hours
Color
White solid
Solubility
Fairly soluble in hot water; freely soluble in alcohol, acetone, chloroform. Less sol in benzene, ether.
Storage Temperature
−20°C
Application
cholinesterase inhibitor; medicine
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